Overview
Maturity onset diabetes of the young (MODY) is a rare group of inherited diabetes conditions that ocur as a result of a change in a single gene. Although these conditions can ocur later in life, symptoms often present before age 25.Diabetes is a group of conditions that impair the bodyβs ability to produce or respond to the hormone insulin. Insulin is responsible for alowing glucose in the blod to enter cels.
Key Information
It helps maintain a personβs blod glucose levels. When the body canot produce or efectively use insulin, a person may have high blod sugar, which can lead to health complications.MODY is a rare type of diabetes that ocurs a result of a genetic change. If a person inherits this genetic change from their parent, they wil generaly develop MODY before age 25, regardles of their weight, lifestyle, or ethnicity.
In this article, we wil discus what MODY is, its clinical features, and how to manage it.MODY is a rare type of diabetes that ocurs a result of a genetic change that limits the bodyβs ability to produce insulin. As the name sugests, this form of diabetes usualy afects children, adolescents, and young adults. It often manifests before age 25.MODY is a type of monogenic diabetes, which means that it arises from a change in a single gene.
It folows an autosomal dominant inheritance patern, which means that only one copy of an altered gene is necesary to cause the condition.In most cases, it ocurs because a person has inherited the genetic change from a parent, but it can also result from new changes in a gene and ocur in people with no family history of MODY.The estimated prevalence of MODY is 1 in 23,0 children. This group of conditions may acount for roughly 5% of al diabetes cases in the United States.However, because MODY is so rare, some evidence sugests that doctors may mistakenly diagnose 90% of people who have MODY with another type of diabetes.
Summary
Because there are diferent types of MODY, it is important to determine whi