Component 4: Comparison of Automated Insulin Delivery Systems (Minimed 670G/770G, t:slim X2 with Control-IQ, and Do It Yourself Loophole)
User-Initiated Settings
Minimed 670G/770G
- Temporary Target: The user can manually set a temporary target blood glucose level to 150 mg/dL for a duration of up to 12 hours.
t:slim X2 with Control-IQ
- Workout Mode: When activated by the user, Workout Mode maintains the current basal rate if the CGM reading is between 140 and 160 mg/dL. If the blood glucose level is predicted to be above 160 mg/dL within 30 minutes, the basal rate is increased. If the blood glucose level is predicted to be above 180 mg/dL within 30 minutes, a correction bolus is suggested (if a bolus has not already been given within the last hour). Basal insulin is decreased if the blood glucose level is predicted to be below 140 mg/dL within 30 minutes, and basal delivery is stopped if the blood glucose level is predicted to be below 80 mg/dL within 30 minutes.
Rest Mode:
- Minimed 670G/770G: Rest Mode is pre-programmed by the user and activates automatically. Configured basal rates are used when the blood glucose level is trending between 112.5 and 120 mg/dL. Basal rates are increased if the blood glucose level is predicted to be above 120 mg/dL within 30 minutes. Correction boluses are not given in this mode. Basal rates are decreased if the blood glucose level is predicted to be below 112.5 mg/dL, and basal delivery is stopped if the blood glucose level is predicted to be below 70 mg/dL within 30 minutes.
t:slim X2 with Control-IQ:
- Sleep Mode: Sleep Mode is pre-programmed by the user and activates automatically. Configured basal rates are used when the blood glucose level is trending between 112.5 and 120 mg/dL. Basal rates are increased if the blood glucose level is predicted to be above 120 mg/dL within 30 minutes. Correction boluses are not given in this mode. Basal rates are decreased if the blood glucose level is predicted to be below 112.5 mg/dL within 30 minutes, and basal delivery is stopped if the blood glucose level is predicted to be below 70 mg/dL within 30 minutes.
Discussion
The Minimed 670G/770G and t:slim X2 with Control-IQ are two commercially available automated insulin delivery systems. Both systems use a continuous glucose monitor (CGM) to measure blood glucose levels and an insulin pump to deliver insulin. The systems use algorithms to adjust the basal insulin rate and deliver correction boluses automatically.
The Minimed 670G/770G has a temporary target mode that allows the user to manually set a target blood glucose level. This can be useful for certain situations, such as before a meal or when exercising. The t:slim X2 with Control-IQ has a workout mode that is designed to help users manage their blood glucose levels during exercise. This mode adjusts the basal insulin rate and delivers correction boluses differently than the standard mode.
Both systems also have a sleep mode that is designed to help users manage their blood glucose levels during sleep. This mode also adjusts the basal insulin rate and delivers correction boluses differently than the standard mode.
Conclusion
The Minimed 670G/770G and t:slim X2 with Control-IQ are two effective automated insulin delivery systems. The choice of which system is best for a particular user will depend on their individual needs and preferences.
