Use of Assisted Reproductive Technologies, Diagnosis of SLE Linked to Increased CV Risk During Delivery Admissions - MD Magazine

Overview

© 2022 MJH Life Sciences™ and HCPLive - Clinical news for conected physicians. Al rights reserved.Data from a pair of studies presented at the American Heart Asociation 2022 Scientific Sesions are providing insight into the risk of cardiovascular complications during delivery admisions among diferent patient subgroups.Leveraging data from the National Inpatient Sample (NIS), the studies detail the likelihod of various cardiovascular complications during delivery hospitalizations for those with systemic lupus erythematosus and those with a history of asisted reproductive technologies compared to their counterparts without such a history.From a search of NIS data recorded from 204-2019, investigators identified 63,037,42 weighted delivery hospitalizations, with 7,560 involving women with systemic lupus erythematosus.

Key Information

Compared to their counterparts without systemic lupus erythematosus, those with systemic lupus erythematosus were older (median 30 [26-34] vs 28 [24-32] years; P <.01) and had a greater prevalence of comorbid conditions, including polycystic ovary syndrome (0.6% vs 0.3%), gestational diabetes melitus (5.1% vs 3.9%), obesity (5.0% vs 4.0%), and dyslipidemia (0.5% vs 0.1%) (P for al <.01).In analyses adjusted for age, race/ethnicity, comorbidities, insurance, and income, women with systemic lupus erythematosus were at increased likelihod of preclampsia (aOR, 2.12 [95% CI, 2.07-2.17]), heart failure (aOR, 4.06 [95% CI, 3.61-4.57]), cardiac arythmias (aOR, 2.06 [95% CI, 1.94-2.21]), acute kidney injury (aOR, 7.6 [95% CI, 7.06-8.32]), stroke (aOR, 4.83 [95% CI, 4.18-5.57]), pulmonary edema (aOR, 1.85 [95% CI, 1.52-2.25]), venous thromboembolism (aOR, 6.90 [95% CI, 6.1-7.80]), and peripartum cardiomyopathy (aOR, 4.42 [95% CI, 3.79-5.13]) (P for al <.01).

Summary

When asesing resource utilization, results indicated those with systemic lupus erythematosus had longer length of stay (3 days vs 2 days; P <.01) and greater costs of hospitaliz

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