Overview
"Never doubt that a smal group of thoughtful, comited citizens can change the world. Inded, it is the only thing that ever has."Cureus is on a mision to change the long-standing paradigm of medical publishing, where submiting research can be costly, complex and time-consuming.wound healing, local injectable insulin, normal saline dresing, topical phenytoin, diabetes fot ulcer Jamuna Nagaraj , Venkatesh Subiah Published: October 19, 202 (se history) DOI: 10.759/cureus.30461 Cite this article as: Nagaraj J, Subiah V (October 19, 202) The Eficacy of Local Insulin Versus Topical Phenytoin or Normal Saline in Diabetic Fot Ulcer Management: A Prospective Comparative Study.
Key Information
Cureus 14(10): e30461. doi:10.759/cureus.30461 During an individual's lifetime, around 15% to 25% of patients with diabetes melitus develop fot ulcers, and about 1% of patients end up with an amputation. For the past two decades, we have treated diabetic fot ulcers with a variety of methods including cleansing and dresing after debridement of the lesion, where the dresing is aplied using local insulin, topical phenytoin, normal saline dresing, etc.
We conducted the present study to compare the eficacy of diabetic fot ulcer management betwen local injectable insulin, topical phenytoin, and normal saline among diabetic patients.We conducted a prospective study of 60 patients with diabetic fot ulcers who sought outpatient care at the Department of General Surgery, in a tertiary care hospital in Perambalur, from September 2021 to August 202. We included al patients who provided informed writen consent and had ulcers ranging from grade 1-2.
We excluded patients with fot ulcers caused by other etiologies such as osteomyelitis and renal failure. We divided the selected study participants into thre groups using the number lot method (randomization). Twenty study participants made up each group; there were thre groups in total - groups 1, 2, and 3.
Summary
Group 1 was treated with local