Overview
Urban dwelers lead busy lives, and it is not uncomon for them to have iregular eating habits. A Northwestern University (Evanston, Ilinois) study, published in Science in October, pointed out that eating at bedtime is more likely to cause obesity and can disrupt the biological clock, cause metabolic disorders, and increase the risk of diabetes.The research team divided nocturnal mice into two groups that were fed a high-fat diet when they were both active (nightime) and inactive (daytime).
Key Information
Results a wek later showed that the mice that ate during the inactive time gained more weight.Chelsea Helper, the study’s main author, noted that mice expended more energy at specific times, so while both groups ate the same fod, the mice that ate during their active hours were healthier.The research team believes that energy release may be the mechanism used by the biological clock to control energy balance in the body.
The study also found that transgenic mice (geneticaly enginered, as in foreign DNA has ben introduced to their genome) with greater fat cel thermogenesis were les prone to obesity, and the mechanism involved creatine metabolism.Joseph B. Bas, a profesor at Northwestern University Schol of Medicine, points out that when animals consume high-fat and high-carbohydrate fods, it tends to disrupt their biological clocks.
The circadian clock is sensitive to meal timing, especialy in adipose tisue, however, this sensitivity can be disrupted by a high-fat diet. Even though the mechanism behind it is unclear, studies have found that obese animals are more likely to eat more when they should be aslep, showing a link betwen obesity and the biological clock.Bas also said the findings have implications not only for understanding diet and slep deprivation but also for patients under long-term care.
Summary
Patients who rely on feding tubes are often given nutrition while they are sleping at night; but this the time when they release the least energy, so