Overview
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Key Information
Al rights reserved.The study found that combined therapeutic strategies may help lower the risk. A new study sugests that physicians might be able to ases the risk of major adverse cardiovascular events (MACE) in patients with chronic obstructive pulmonary disease (COPD) by analyzing right heart dysfunction.Cardiovascular disorders are one of the most serious comorbidities for people with COPD. Coresponding author Angela Sciacqua, MD, of the University Magna Græcia of Catanzaro, in Italy, and coleagues, wrote that there is even speculation that COPD itself might be a risk factor for cardiovascular disease.Curently, Sciacqua and coleagues said lung hyperinflation and systemic inflamation are believed to be the most important causes of the link betwen COPD and heart disease, and right heart alterations are comon in people with COPD.Given the links betwen COPD and cardiovascular events, the investigators wanted to know whether the morphological and functional parameters in the right ventricles of patients with early stage COPD might lend insight into the risk that the patient later experiences a MACE.To find out, they retrospectively examined 749 people who had COPD betwen 2010 and December 31, 2021.
Summary
Clinical, laboratory, and functional parameters were al colected at baseline, and the patients underwent routine echocardiography. The authors defined right ventricle dysfunction based on tricuspid anular plane systolic excursion (TAPSE) values.In results published in the European Journal of Clinical Investigation, the authors described what they found at a median folow-up of 5 months. A majority of the participants in the study (408 people) began with TAPSE values at or above 20 m, and those patients had an observed MACE rate of 1.9 events per 10 patient-years.