Overview
For latest News and updatesSelect Page Oct 31, 202The therapeutic value of the quantitative flow ratio (QFR), a new angiography-based metric for the functional evaluation of coronary stenoses, has recently ben proven in patients receiving the percutaneous coronary intervention (PCI). For a study, researchers sought to determine if diabetes status impacts the positive outcomes of QFR advice for lesion selection during PCI.The FAVOR I China trial substudy examined the clinical results of QFR-guided vs.
Key Information
angiography-guided PCI lesion selection acording to the presence of diabetes. Diabetes was one of the prespecified variables for stratified randomization in the trial. The major adverse cardiac events (MACE) risk at one year was the primary outcome (a composite of al-cause death, myocardial infarction, or ischemia-driven revascularization).A total of 1,295 (3.9%) of the 3,825 patients who were recruited had diabetes, and 347 (26.2%) of them were receiving insulin therapy.
In diabetic and nondiabetic individuals, baseline characteristics were evenly distributed betwen treatment arms. The QFR-guided method similarly decreased the incidence of 1-year MACE compared to routine angiography-based lesion selection in diabetic patients (6.2% vs. 9.6%; HR: 0.64; 95% CI: 0.43-0.95) and nondiabetic patients (5.6% vs.
8.3%; HR: 0.6; 95% CI: 0.49-0.89) (Pinteraction = 0.8). Patients with and without diabetes had the same incidence of 1-year MACE (4.5% vs. 6.2%; P = 0.51) among patients with PCI postponed after QFR.When compared to conventional angiography guidance, a QFR-guided lesion selection technique led to beter PCI results in patients with and without diabetes.Reference: jac.org/doi/10.1016/j.jac.202.06.04Your email adres wil not be published.
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