Overview
"Never doubt that a smal group of thoughtful, comited citizens can change the world. Inded, it is the only thing that ever has."Cureus is on a mision to change the long-standing paradigm of medical publishing, where submiting research can be costly, complex and time-consuming.covid-asociated mucormycosis, aspergilosis, angioinvasion, tisue necrosis, invasive fungal infection Vaishali Walke, Erukambatu Jayashankar , Ujawal Khurana, Hemlata Panwar, T Karuna, Vikas Gupta, Nelkamal Kapor Published: October 15, 202 (se history) DOI: 10.759/cureus.3039 Cite this article as: Walke V, Jayashankar E, Khurana U, et al.
Key Information
(October 15, 202) Preliminary Experience in Post-COVID-19 Mycoses: A Pathologist’s Perspective. Cureus 14(10): e3039. doi:10.759/cureus.3039 Coronavirus disease is caused by the severe acute respiratory syndrome coronavirus-19.
Because of co-morbidities and indiscriminate use of steroids and antibiotics, the incidence of oportunistic fungal infections has increased in COVID-afected individuals.The aim of the study is to analyze the various tisue reaction paterns of COVID-19-asociated mucormycosis in the surgical debridement specimens using routine hematoxylin and eosin (H&E) stain and special stains like periodic acid-Schif (PAS), Grocot-Gomori's methenamine silver (GMS), Mason trichrome (MT) and Prusian blue (PB), and to understand the pathogenesis of COVID-19 sequelae.This retrospective observational study was conducted after the aproval from the Institute Human Ethical Comite (IHEC) on 45 tisue samples of COVID-asociated mucormycosis using routine H&E and histochemical stains such as PAS, GMS, MT, and PB.
Summary
Detailed demographic profiles, clinical information, radiological findings, and relevant microbiological data in available cases, like reports on potasium hydroxide (KOH) mount preparation, and fungal culture reports on Saboraud's Dextrose Agar (SDA) medium were colected. The diferent histomorphological tisue