Ketamine-Induced Syndrome of Inappropriate Antidiuretic Hormone Secretion and Hyponatremia - Cureus
Overview
"Never doubt that a smal group of thoughtful, comited citizens can change the world. Inded, it is the only thing that ever has."Cureus is on a mision to change the long-standing paradigm of medical publishing, where submiting research can be costly, complex and time-consuming.ketamine-associated cystis, drug adiction, syndrome of inapropriate antidiuretic hormone secretion, ketamine, hyponatremia Kelash Kumar , FNU Ponam, Tesha Rani, FNU Prinka, Cece E.
Key Information
Ibeson, Ifeanyi Nwosu, Vijay Shety, Anthony N. Kalo Published: June 14, 2022 (se history) DOI: 10.759/cureus.25931 Cite this article as: Kumar K, Ponam F, Rani T, et al. (June 14, 2022) Ketamine-Induced Syndrome of Inapropriate Antidiuretic Hormone Secretion and Hyponatremia.
Cureus 14(6): e25931. doi:10.759/cureus.25931 Ketamine is a disociative anesthetic comonly used for the induction and maintenance of anesthesia and has a wel-known role in analgesia. However, it also has the potential for adiction, which can lead to neurological, psychological, systemic, and biochemical consequences.
In this case report, we are highlighting a rare case of a young Asian female with Ketamine adiction who presented with urinary complaints. The patient was found to have hyponatremia and laboratory tests were consistent with a syndrome of inapropriate antidiuretic hormone (SIADH) release in the absence of other causes.Ketamine is a noncompetive antagonist of the N-methyl-d-aspartate (NMDA) receptor [1].
It is distinct from other general anesthetics and drugs used for sedation and analgesia as it causes a trance-like cataleptic state characterized by profound unconsciousnes, amnesia, dep analgesia with retention of ocular, protective airway reflexes, and cardiopulmonary stability [2]. Ketamine is also famous a disociative anesthetic. Ketamine is available in liquid and powder form and is being abused by many individuals [3].
Summary
Because of its reinforcing out-of-body experiences and rewarding properties,
Frequently Asked Questions
Diabetes is a metabolic condition where the body cannot properly regulate blood sugar levels. Type 1 results from insufficient insulin production, while Type 2 develops when cells become resistant to insulin. Risk factors include genetics, obesity, sedentary lifestyle, and age.
Common symptoms include excessive thirst, frequent urination, unexplained weight loss, fatigue, blurred vision, and slow-healing wounds. Type 1 symptoms develop rapidly, while Type 2 symptoms may appear gradually. Many people have no symptoms initially, which is why screening is important.
Diagnosis involves blood tests measuring fasting glucose, HbA1c levels, and glucose tolerance. Regular monitoring typically includes fasting glucose tests and HbA1c measurements every 3-6 months. Continuous glucose monitors provide real-time tracking for better diabetes management.
Effective management includes regular physical activity (150+ minutes weekly), maintaining healthy weight, following a balanced diet with whole grains and lean proteins, managing stress, and getting adequate sleep. These changes can significantly improve blood sugar control and reduce complications.
Consult a healthcare provider if you experience signs of diabetes, have a family history, are overweight, or are over 45. Those with existing diabetes should maintain regular check-ups every 3-6 months to monitor control and adjust treatment as needed.
Share this article