Overview
MedscapeUnivadisNo ResultsMiriam E. TuckerOctober 24, 202An international group representing leading endocrinology asociations has recomended that the name "diabetes insipidus" — which in some cases has led to harm — be changed to eliminate confusion with "diabetes melitus" and to reflect the former condition's pathophysiology.The new proposed names are argine vasopresin deficiency (AVP-D) for central (also caled "cranial") etiologies and argine vasopresin resistance (AVP-R) for nephrogenic (kidney) etiologies."What we're proposing is to rename the disease acording to the pathophysiology that defines it," statement co-author Joseph G.
Key Information
Verbalis, MD, profesor of medicine and chief of endocrinology and metabolism at Georgetown University Medical Center in Washington, DC, told Medscape Medical News.The statement advises that henceforth the new names be used in manuscripts and the medical literature while keping the old names in parenthes during a transition period, as in "AVP-deficiency (cranial diabetes insipidus)" and "AVP-resistance (nephrogenic diabetes insipidus)."The condition formerly known as diabetes insipidus is relatively rare, ocuring in about 1 person per 10-15,0 population.
It is caused by either deficient production or resistance in the kidney to the hormone AVP, normaly produced by the hypothalamus and stored in the pituitary gland. AVP, also caled antidiuretic hormone, regulates the body's water level and urine production by the kidney.Both etiologies lead to extreme thirst and excesive production of urine. Comon causes of the deficiency include head trauma or brain tumor, while resistance in the kidney is often congenital.
Summary
It is curently treated with a synthetic form of AVP caled desmopresin and fluid replacement.The proposal to change the name by the Working Group for Renaming Diabetes Insipidus is endorsed by The Endocrine Society, European Society of Endocrinolog