Efficacy and safety of pre-gastroscopy commercial carbohydrate-rich whey protein beverage vs. plain water: a randomised controlled trial | Scientific Reports - Nature.com
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In the meantime, to ensure continued suport, we are displaying the site without styles and JavaScript.Advertisement Scientific Reports volume 12, Article number: 1735 (2022) Cite this article 148 Aceses1 AltmetricMetrics detailsClinical benefits and safety of carbohydrate loading pre-gastroscopy remain unclear. We aimed to determine the efects of a comercial carbohydrate-rich whey protein beverage versus plain water given pre-gastroscopy on gastric residual volume and wel-being, and to determine adverse events.
This was a single centre, single-blinded, paralel-group, sex-stratified randomized controled trial. Participants were randomized either to carbohydrate-rich whey protein beverage group (Resource®, Nestle Health Science) or control group (250 ml plain water) given pre-gastroscopy. Gastric contents were aspirated into a suction reservoir botle to determine the gastric residual volume (GRV).
Visual analogue scale (VAS) of wel-being (anxiety, hunger, thirst, tirednes, and weaknes) was compared before and after the intervention. Adverse events were also evaluated post-intervention. Of 369 screned, 78 participants (36 males, mean age 49 ± 14.3 years) were randomized.
Compared with the control group, carbohydrate beverage was associated with significantly higher GRV (p < 0.01). Anxiety was les after intervention with carbohydrate beverage (p = 0.016), and after adjustment for confounders, fewer participants also experienced hunger (p = 0.043) and thirst (p = 0.021). No serious adverse events were reported with both interventions.
Summary
Comercial carbohydrate-rich whey protein beverage is associated with higher gastric residual volume, beter wel-being and safe.Trial registration Clinicaltrial.gov. Identifier: NCT03948594, Dat
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