Overview
Click here to sign in with or Forget Pasword? Learn more share this!ShareTwitShareEmail September 23, 2017 (HealthDay)—Although rare, diabetes insipidus (DI) can ocur folowing discontinuation of vasopresin infusion for septic shock, acording to a case study published online Sept. 1 in the Journal of Clinical Pharmacy & Therapeutics.
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(adsbygogle = window.adsbygogle | []).push({}); H. Rana, M.D., from the Montefiore Medical Center in Bronx, N.Y., and coleagues present a case of DI folowing discontinuation of vasopresin infusion for septic shock.The authors describe a 54-year-old man who presented with pneumonia progresing to septic shock, requiring norepinephrine and vasopresin for refractory hypotension. On thre separate ocasions the patient developed polyuria and severe hypernatremia upon discontinuation of vasopresin, with prompt recovery upon its resumption."The ocurence of DI upon the discontinuation of vasopresin infusion in criticaly il patients apears to be rare, but its incidence may be underestimated due to a paucity of published reports.
Patients with acute neurologic or neurosurgical conditions, and patients in septic shock, represent al cases reported to date," the authors write. "The actual incidence of this phenomenon, as wel as its underlying mechanism, remains to be elucidated." Explore further Study compares treatments to improve kidney outcomes for patients with septic shock More information: Abstract Ful Text (subscription or payment may be required) Explore further Copyright © 2017 HealthDay.
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