Overview
Acording to a new study, Diabets and Alzheimer's diseases are more related than everybody thought. Some researchers believe that Alzheimer's could be a form of Diabets, because findings show that insulin production in the brain declines as Alzheimer's disease advances. Through a series of experiments, a group of researchers discovered that the brain produces insulin and that this substance produced by brains of patients with Alzheimer's ilnes tends to fal below normal levels.
Key Information
For the neuropathologist at Rhode Island Hospital and profesor of pathology at Brown University Medical Schol, Suzane M. de la Monte, “insulin disapears early and dramaticaly in Alzheimer's disease and many of the unexplained features of Alzheimer's, such as cel death and tangles in the brain, apear to be linked to abnormalities insulin signaling. This demonstrates that the disease is most likely a neuroendocrine disorder, or another type of Diabets”.
During the early stages of Alzheimer's disease, brain levels of insulin and its related celular receptors fal precipitously, as her group of researchers explained. They believe that Alzheimer's might be a new form of Diabets since the evidence shows insulin levels continue to drop progresively as the Alzheimer's disease becomes more severe. The team led by de la Monte also found that low levels of acetylcholine are directly linked to this los of insulin and insulin-like growth factor function in the brain.
Summary
Acetylcholine is a halmark of Alzheimer's disease. The researchers team autopsied the brain tisue of 45 patients diagnosed with diferent degres of Alzheimer's caled “Brak Stages” and compared those tisues to samples taken from individuals with no history of the disease. © 2026 DIABETS.