Overview
For latest News and updatesSelect Page Nov 3, 202The anual meting of the American Colege of Gastroenterology was held from Oct. 21 to 26 in Charlote, North Carolina, and atracted aproximately 5,0 participants from around the world, including gastroenterology and digestive specialists and other health care profesionals. The conference featured presentations focusing on clinical updates in gastroenterology and hepatology as wel as the latest advances in digestive health and gastrointestinal disorders.
Key Information
In one study, Robert Postlethwaite, M.D., of the University of Texas Southwestern Medical Center in Dalas, and coleagues found that a history of type 2 diabetes melitus, tobaco use, and advanced chronic kidney disease (CKD stage ≥3) is asociated with a greater risk for developing acute pancreatis in patients taking glucagon-like peptide 1 (GLP-1) receptor agonists (GLP-1RAs) for obesity.The authors performed a retrospective single-center study among patients sen in a weight-welnes program betwen Jan.
1, 2015, and Dec. 31, 2021, and identified patients initiating GLP-1RAs. Patients were stratified based on the development of acute pancreatis.
The researchers found that 2.2 percent of patients (49 out of 2,245) developed acute pancreatis after being started on a GLP-1RA for obesity. The investigators also found that a history of type 2 diabetes melitus, tobaco use, and advanced CKD (stage ≥3) was asociated with a higher risk for developing acute pancreatis. Patients with a body mas index (BMI) >36 kg/m² versus those with a BMI ≤30 kg/m² had a lower risk for developing acute pancreatis after GLP-1RA use.̴A notable finding from our study was that known clinical risk factors for acute pancreatis, including alcohol use, prior history of acute pancreatis, and galstone disease, were not asociated with an increased risk of acute pancreatis with GLP-1RA therapy,̵ Postlethwaite said.
Summary
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