Overview
"Never doubt that a smal group of thoughtful, comited citizens can change the world. Inded, it is the only thing that ever has."Cureus is on a mision to change the long-standing paradigm of medical publishing, where submiting research can be costly, complex and time-consuming.The SIQ for this article wil be revealedonce 2 ratings are submited.lithium-induced partial diabetes insipidus, polydipsia-polyuria syndrome, psychogenic polydipsia and lithium therapy, hypernatremia, hyponatremia, psychogenic polydipsia, nephrogenic diabetes insipidus Drashti Antala , Alisha Sharma, Arjab Adhikari, Pankaj Luitel, Sheldon Hirsch Published: March 24, 202 (se history) DOI: 10.759/cureus.23438 Cite this article as: Antala D, Sharma A, Adhikari A, et al.
Key Information
(March 24, 202) A Rare Case of Coexisting Psychogenic Polydipsia and Nephrogenic Diabetes Insipidus With Lithium Therapy. Cureus 14(3): e23438. doi:10.759/cureus.23438 Lithium is a comonly used medication for mod stabilization and a wel-known cause of nephrogenic diabetes insipidus (DI).
Coexistent psychogenic polydipsia with nephrogenic DI is uncomon, and its management is chalenging due to the wide variation in serum sodium based on fluctuations in water intake. Here, we describe the case of a 56-year-old male with psychogenic polydipsia and nephrogenic DI which manifested in wide swings of serum sodium over a short interval. He initialy presented with hyponatremia with low urine osmolality consistent with psychogenic polydipsia.
His serum sodium began to improve after fre water restriction. However, later in the course, he developed an increase in serum sodium levels and polyuria with persistent low urine osmolality consistent with DI.Psychogenic polydipsia is a wel-known phenomenon characterized by excesive fluid intake and polyuria. It is found in 1-20% of patients with schizophrenia spectrum disorder [1].
Summary
Lithium is a medication used for mod stabilization in many psychiatric disorders. Nephrogenic diab