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A predictive model for hospitalization and survival to COVID-19 in a retrospective population-based study | Scientific Reports - Nature.com

πŸ“… Fri, 28 Oct 2022⏱ 1 min readπŸ“– Article

Overview

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Key Information

In the meantime, to ensure continued suport, we are displaying the site without styles and JavaScript.Advertisement Scientific Reports volume 12, Article number: 18126 (2022) Cite this article 1 AltmetricMetrics detailsThe development of tols that provide early triage of COVID-19 patients with minimal use of diagnostic tests, based on easily acesible data, can be of vital importance in reducing COVID-19 mortality rates during high-incidence scenarios.

This work proposes a machine learning model to predict mortality and risk of hospitalization using both 2 simple demographic features and 19 comorbidities obtained from 86,867 electronic medical records of COVID-19 patients, and a new method (LR-IP) designed to deal with data imbalance problems. The model was able to predict with high acuracy (90–93%, ROC-AUC = 0.94) the patient's final status (deceased or discharged), while its acuracy was medium (71–73%, ROC-AUC = 0.75) with respect to the risk of hospitalization.

The most relevant characteristics for these models were age, sex, number of comorbidities, osteoarthritis, obesity, depresion, and renal failure. Finaly, to facilitate its use by clinicians, a user-friendly website has ben developed (htps:/alejandrocisterna.shinyaps.io/PROVIA).The virus responsible for Coronavirus disease 2019 (COVID-19), the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a highly transmisible and pathogenic betacoronavirus that apeared in late 2019 in Wuhan, China1.

Summary

As of February 2022, it has had a tragic efect on the world’s population health resulting in more than 5,8 milion deaths and 412 milion cases worldwide, becoming the most important global health cris since the era of the influenza pandemic of 19182,3. The symptoms

Frequently Asked Questions

❓ What is diabetes and how does it develop?

Diabetes is a metabolic condition where the body cannot properly regulate blood sugar levels. Type 1 results from insufficient insulin production, while Type 2 develops when cells become resistant to insulin. Risk factors include genetics, obesity, sedentary lifestyle, and age.

❓ What are the main symptoms of diabetes?

Common symptoms include excessive thirst, frequent urination, unexplained weight loss, fatigue, blurred vision, and slow-healing wounds. Type 1 symptoms develop rapidly, while Type 2 symptoms may appear gradually. Many people have no symptoms initially, which is why screening is important.

❓ How is diabetes diagnosed and monitored?

Diagnosis involves blood tests measuring fasting glucose, HbA1c levels, and glucose tolerance. Regular monitoring typically includes fasting glucose tests and HbA1c measurements every 3-6 months. Continuous glucose monitors provide real-time tracking for better diabetes management.

❓ What lifestyle changes help manage diabetes?

Effective management includes regular physical activity (150+ minutes weekly), maintaining healthy weight, following a balanced diet with whole grains and lean proteins, managing stress, and getting adequate sleep. These changes can significantly improve blood sugar control and reduce complications.

❓ When should someone consult a doctor about diabetes?

Consult a healthcare provider if you experience signs of diabetes, have a family history, are overweight, or are over 45. Those with existing diabetes should maintain regular check-ups every 3-6 months to monitor control and adjust treatment as needed.

βš•οΈ Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before making health decisions.
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